Exacerbated corneal inflammation and neovascularization in the HO-2 null mice is ameliorated by biliverdin.

Bellner, Lars; Vitto, Marco; Patil, Kiran A; Dunn, Michael W; Regan, Raymond; Laniado-Schwartzman, Michal

Bellner, Lars; Vitto, Marco; Patil, Kiran A; Dunn, Michael W; Regan, Raymond; Laniado-Schwartzman, Michal.

Affiliation

Bellner L; Department of Pharmacology, New York Medical College, Valhalla, NY 10595, USA.

Exp Eye Res ; 87(3): 268-78, 2008 Sep.

Article in En | MEDLINE | ID: mdl-18602389

Subject(s)

Biliverdine/therapeutic use; Corneal Neovascularization/prevention & control; Keratitis/prevention & control; Animals; Cornea/enzymology; Corneal Neovascularization/enzymology; Corneal Neovascularization/pathology; Disease Progression; Drug Evaluation, Preclinical; Female; Heme Oxygenase (Decyclizing)/deficiency; Heme Oxygenase (Decyclizing)/metabolism; Heme Oxygenase (Decyclizing)/physiology; Heme Oxygenase-1/metabolism; Keratitis/enzymology; Keratitis/pathology; Male; Mice; Mice, Knockout; Peroxidase/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biliverdine / Corneal Neovascularization / Keratitis Limits: Animals Language: En Journal: Exp Eye Res Year: 2008 Document type: Article Affiliation country: United States Country of publication: United kingdom

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