Adenine/analogs & derivatives; Anti-HIV Agents/administration & dosage; HIV Integrase Inhibitors/administration & dosage; Organophosphonates/administration & dosage; Pyrrolidinones/administration & dosage; Reverse Transcriptase Inhibitors/administration & dosage; Adenine/administration & dosage; Adenine/pharmacokinetics; Adenine/therapeutic use; Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents/pharmacokinetics; Anti-HIV Agents/therapeutic use; Benzoxazines/administration & dosage; Benzoxazines/therapeutic use; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections/drug therapy; HIV Infections/virology; HIV Integrase Inhibitors/pharmacokinetics; HIV Integrase Inhibitors/therapeutic use; HIV-1/drug effects; Humans; Lamivudine/administration & dosage; Lamivudine/therapeutic use; Male; Middle Aged; Organophosphonates/pharmacokinetics; Organophosphonates/therapeutic use; Pyrrolidinones/pharmacokinetics; Pyrrolidinones/therapeutic use; Raltegravir Potassium; Reverse Transcriptase Inhibitors/pharmacokinetics; Reverse Transcriptase Inhibitors/therapeutic use; Tenofovir; Treatment Outcome