Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects.

Reyna, Sara M; Ghosh, Sangeeta; Tantiwong, Puntip; Meka, C S Reddy; Eagan, Phyllis; Jenkinson, Christopher P; Cersosimo, Eugenio; Defronzo, Ralph A; Coletta, Dawn K; Sriwijitkamol, Apiradee; Musi, Nicolas

Reyna, Sara M; Ghosh, Sangeeta; Tantiwong, Puntip; Meka, C S Reddy; Eagan, Phyllis; Jenkinson, Christopher P; Cersosimo, Eugenio; Defronzo, Ralph A; Coletta, Dawn K; Sriwijitkamol, Apiradee; Musi, Nicolas.

Affiliation

Reyna SM; Diabetes Division, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.

Diabetes ; 57(10): 2595-602, 2008 Oct.

Article in En | MEDLINE | ID: mdl-18633101

Subject(s)

Insulin Resistance/physiology; Muscle, Skeletal/metabolism; Signal Transduction/physiology; Toll-Like Receptor 4/physiology; Adult; Blotting, Western; Cells, Cultured; Diabetes Mellitus, Type 2/genetics; Diabetes Mellitus, Type 2/metabolism; Diabetes Mellitus, Type 2/physiopathology; Fatty Acids, Nonesterified/pharmacology; Female; Gene Expression/drug effects; Humans; I-kappa B Proteins/metabolism; Male; Middle Aged; Muscle, Skeletal/cytology; Muscle, Skeletal/drug effects; NF-KappaB Inhibitor alpha; NF-kappa B/metabolism; Obesity/genetics; Obesity/metabolism; Obesity/physiopathology; Reverse Transcriptase Polymerase Chain Reaction; Toll-Like Receptor 4/genetics; Toll-Like Receptor 4/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin Resistance / Signal Transduction / Muscle, Skeletal / Toll-Like Receptor 4 Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Diabetes Year: 2008 Document type: Article Affiliation country: United States

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