PICK1 uncoupling from mGluR7a causes absence-like seizures.

Bertaso, Federica; Zhang, Chuansheng; Scheschonka, Astrid; de Bock, Frédéric; Fontanaud, Pierre; Marin, Philippe; Huganir, Richard L; Betz, Heinrich; Bockaert, Joël; Fagni, Laurent; Lerner-Natoli, Mireille

Bertaso, Federica; Zhang, Chuansheng; Scheschonka, Astrid; de Bock, Frédéric; Fontanaud, Pierre; Marin, Philippe; Huganir, Richard L; Betz, Heinrich; Bockaert, Joël; Fagni, Laurent; Lerner-Natoli, Mireille.

Affiliation

Bertaso F; CNRS UMR5203, Institut de Génomique Fonctionnelle, Montpellier, France, INSERM, U661, Montpellier, France and Université Montpellier, 1, 2, 141 rue de Cardonille, 34094 Montpellier, Cedex 5, France.

Nat Neurosci ; 11(8): 940-8, 2008 Aug.

Article in En | MEDLINE | ID: mdl-18641645

Subject(s)

Carrier Proteins/metabolism; Disease Models, Animal; Epilepsy, Absence/physiopathology; Nuclear Proteins/metabolism; Receptors, Metabotropic Glutamate/metabolism; Animals; Carrier Proteins/genetics; Cell Cycle Proteins; Cells, Cultured; Electrodes, Implanted; Electroencephalography/drug effects; Epilepsy, Absence/genetics; Epilepsy, Absence/metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Transgenic; Nuclear Proteins/genetics; Peptides/pharmacology; Phenotype; Protein Binding/drug effects; Protein Structure, Tertiary/drug effects; Protein Subunits/genetics; Protein Subunits/metabolism; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate/genetics; Recombinant Fusion Proteins/genetics; Recombinant Fusion Proteins/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / Carrier Proteins / Epilepsy, Absence / Receptors, Metabotropic Glutamate / Disease Models, Animal Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Nat Neurosci Journal subject: NEUROLOGIA Year: 2008 Document type: Article Affiliation country: France Country of publication: United States

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