Evidence for multiple effects of ProTxII on activation gating in Na(V)1.5.

Edgerton, Gabrielle B; Blumenthal, Kenneth M; Hanck, Dorothy A

Edgerton, Gabrielle B; Blumenthal, Kenneth M; Hanck, Dorothy A.

Affiliation

Edgerton GB; Committee on Neurobiology, University of Chicago, 5841 South Maryland Avenue, MC6094, Chicago, IL 60637, USA.

Toxicon ; 52(3): 489-500, 2008 Sep 01.

Article in En | MEDLINE | ID: mdl-18657562

Subject(s)

Ion Channel Gating/drug effects; Muscle Proteins/metabolism; Sodium Channels/metabolism; Spider Venoms/pharmacology; Animals; Dose-Response Relationship, Drug; Humans; Muscle Proteins/genetics; Mutation; NAV1.5 Voltage-Gated Sodium Channel; Sodium Channels/genetics; Spider Venoms/chemistry; Spider Venoms/metabolism; Spiders/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spider Venoms / Sodium Channels / Ion Channel Gating / Muscle Proteins Limits: Animals / Humans Language: En Journal: Toxicon Year: 2008 Document type: Article Affiliation country: United States Country of publication: United kingdom

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