Peripheral blood mononuclear cell infiltration and neuroinflammation in the HexB-/- mouse model of neurodegeneration.

Kyrkanides, Stephanos; Miller, Ann W; Miller, Jen-Nie H; Tallents, Ross H; Brouxhon, Sabine M; Olschowka, Mallory E; O'Banion, M Kerry; Olschowka, John A

Kyrkanides, Stephanos; Miller, Ann W; Miller, Jen-Nie H; Tallents, Ross H; Brouxhon, Sabine M; Olschowka, Mallory E; O'Banion, M Kerry; Olschowka, John A.

Affiliation

Kyrkanides S; Department of Neurobiology & Anatomy, School of Medicine & Dentistry, University of Rochester Rochester NY 14642, USA. Stephanos_kyrkanides@urmc.rochester.edu

J Neuroimmunol ; 203(1): 50-7, 2008 Oct 15.

Article in En | MEDLINE | ID: mdl-18657867

Subject(s)

Encephalitis/immunology; Hexosaminidase B/immunology; Leukocytes, Mononuclear/immunology; Nerve Degeneration/immunology; Sandhoff Disease/immunology; Animals; Apoptosis/immunology; Disease Models, Animal; Encephalitis/metabolism; Encephalitis/pathology; Female; G(M2) Ganglioside/metabolism; Hexosaminidase B/genetics; Leukocytes, Mononuclear/pathology; Male; Mice; Mice, Knockout; Microglia/immunology; Microglia/pathology; Nerve Degeneration/metabolism; Nerve Degeneration/pathology; Receptors, CCR2/genetics; Receptors, CCR2/immunology; Sandhoff Disease/metabolism; Sandhoff Disease/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sandhoff Disease / Leukocytes, Mononuclear / Encephalitis / Hexosaminidase B / Nerve Degeneration Limits: Animals Language: En Journal: J Neuroimmunol Year: 2008 Document type: Article Affiliation country: United States Country of publication: Netherlands

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