Antiproliferative and apoptotic effects of two new Pd(II) methylsarcosinedithiocarbamate derivatives on human acute myeloid leukemia cells in vitro.

Aldinucci, Donatella; Cattaruzza, Lara; Lorenzon, Debora; Giovagnini, Lorena; Fregona, Dolores; Colombatti, Alfonso

Aldinucci, Donatella; Cattaruzza, Lara; Lorenzon, Debora; Giovagnini, Lorena; Fregona, Dolores; Colombatti, Alfonso.

Affiliation

Aldinucci D; Experimental Oncology 2, Centro di Riferimento Oncologico, IRCCS, Aviano (PN), Italy. daldinucci@cro.it

Oncol Res ; 17(3): 103-13, 2008.

Article in En | MEDLINE | ID: mdl-18669162

Subject(s)

Apoptosis/drug effects; Granulocyte Precursor Cells/pathology; Leukemia, Promyelocytic, Acute/drug therapy; Organometallic Compounds/pharmacology; Cell Proliferation/drug effects; Colony-Forming Units Assay; Cytoskeletal Proteins/chemical synthesis; Granulocyte Precursor Cells/drug effects; HL-60 Cells; Hematopoietic Stem Cells/drug effects; Hematopoietic Stem Cells/pathology; Humans; K562 Cells; Leukemia, Promyelocytic, Acute/blood; Leukemia, Promyelocytic, Acute/pathology; Organometallic Compounds/chemical synthesis; Palladium/chemistry; Proto-Oncogene Proteins c-bcl-2/blood; Thiocarbamates/chemical synthesis; bcl-2-Associated X Protein/blood

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Collection: 01-internacional Database: MEDLINE Main subject: Organometallic Compounds / Leukemia, Promyelocytic, Acute / Apoptosis / Granulocyte Precursor Cells Limits: Humans Language: En Journal: Oncol Res Journal subject: NEOPLASIAS Year: 2008 Document type: Article Affiliation country: Italy Country of publication: United States

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