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Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel.
Jing, Xianghong; Ma, Chunlong; Ohigashi, Yuki; Oliveira, Fernando A; Jardetzky, Theodore S; Pinto, Lawrence H; Lamb, Robert A.
Affiliation
  • Jing X; Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, IL 60208-3500, USA.
Proc Natl Acad Sci U S A ; 105(31): 10967-72, 2008 Aug 05.
Article in En | MEDLINE | ID: mdl-18669647

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Amantadine / Models, Molecular / Viral Matrix Proteins Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2008 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Amantadine / Models, Molecular / Viral Matrix Proteins Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2008 Document type: Article Affiliation country: United States Country of publication: United States