Methadone ameliorates multiple-low-dose streptozotocin-induced type 1 diabetes in mice.

Amirshahrokhi, K; Dehpour, A R; Hadjati, J; Sotoudeh, M; Ghazi-Khansari, M

Amirshahrokhi, K; Dehpour, A R; Hadjati, J; Sotoudeh, M; Ghazi-Khansari, M.

Affiliation

Amirshahrokhi K; Department of Pharmacology School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Toxicol Appl Pharmacol ; 232(1): 119-24, 2008 Oct 01.

Article in En | MEDLINE | ID: mdl-18671992

Subject(s)

Diabetes Mellitus, Experimental/drug therapy; Diabetes Mellitus, Type 1/drug therapy; Hypoglycemic Agents/pharmacology; Immunosuppressive Agents/pharmacology; Methadone/pharmacology; Pancreas/drug effects; Receptors, Opioid, mu/agonists; Animals; Blood Glucose/drug effects; Cytokines/metabolism; Diabetes Mellitus, Experimental/immunology; Diabetes Mellitus, Experimental/metabolism; Diabetes Mellitus, Type 1/chemically induced; Diabetes Mellitus, Type 1/immunology; Diabetes Mellitus, Type 1/metabolism; Drug Administration Schedule; Injections, Intraperitoneal; Insulin/blood; Mice; Naltrexone/pharmacology; Narcotic Antagonists/pharmacology; Pancreas/immunology; Pancreas/metabolism; Pancreas/pathology; Receptors, Opioid, mu/metabolism; Streptozocin/administration & dosage; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreas / Receptors, Opioid, mu / Diabetes Mellitus, Experimental / Diabetes Mellitus, Type 1 / Hypoglycemic Agents / Immunosuppressive Agents / Methadone Type of study: Prognostic_studies Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 2008 Document type: Article Affiliation country: Iran Country of publication: United States

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