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Application of molecular modeling for prediction of substrate specificity in cytochrome P450 1A2 mutants.
Tu, Youbin; Deshmukh, Rahul; Sivaneri, Meena; Szklarz, Grazyna D.
Affiliation
  • Tu Y; Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, P.O. Box 9530, Morgantown, WV 26506-9530, USA.
Drug Metab Dispos ; 36(11): 2371-80, 2008 Nov.
Article in En | MEDLINE | ID: mdl-18703643
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Models, Molecular / Mutagenesis, Site-Directed / Cytochrome P-450 CYP1A2 Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Drug Metab Dispos Journal subject: FARMACOLOGIA Year: 2008 Document type: Article Affiliation country: United States Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Models, Molecular / Mutagenesis, Site-Directed / Cytochrome P-450 CYP1A2 Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Drug Metab Dispos Journal subject: FARMACOLOGIA Year: 2008 Document type: Article Affiliation country: United States Country of publication: United States