Tetrahdroxysqualene from Rhus taitensis shows antimycobacterial activity against Mycobacterium tuberculosis.

Noro, Jeffrey C; Barrows, Louis R; Gideon, Osia G; Ireland, Chris M; Koch, Michael; Matainaho, Teatulohi; Piskaut, Pius; Pond, Christopher D; Bugni, Tim S

Noro, Jeffrey C; Barrows, Louis R; Gideon, Osia G; Ireland, Chris M; Koch, Michael; Matainaho, Teatulohi; Piskaut, Pius; Pond, Christopher D; Bugni, Tim S.

Affiliation

Noro JC; School of Medicine and Health Sciences, University of Papua New Guinea, P.O. Box 5623, Boroko, NCD, Papua New Guinea.

J Nat Prod ; 71(9): 1623-4, 2008 Sep.

Article in En | MEDLINE | ID: mdl-18710283

Subject(s)

Antitubercular Agents; Mycobacterium tuberculosis/drug effects; Plants, Medicinal/chemistry; Rhus/chemistry; Squalene; Antitubercular Agents/chemistry; Antitubercular Agents/isolation & purification; Antitubercular Agents/pharmacology; Drug Resistance, Bacterial/drug effects; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Nuclear Magnetic Resonance, Biomolecular; Papua New Guinea; Plant Leaves/chemistry; Plant Stems/chemistry; Squalene/analogs & derivatives; Squalene/chemistry; Squalene/isolation & purification; Squalene/pharmacology; T-Lymphocytes/drug effects; Tuberculosis/drug therapy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plants, Medicinal / Squalene / Rhus / Mycobacterium tuberculosis / Antitubercular Agents Limits: Humans Language: En Journal: J Nat Prod Year: 2008 Document type: Article Affiliation country: Papua New Guinea Country of publication: United States

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