Interleukin-4/metabolism; Protein Tyrosine Phosphatase, Non-Receptor Type 1/biosynthesis; STAT6 Transcription Factor/metabolism; Signal Transduction/physiology; Animals; Enzyme Inhibitors/pharmacology; Gene Expression Regulation, Enzymologic/drug effects; Gene Expression Regulation, Enzymologic/genetics; Gene Expression Regulation, Enzymologic/immunology; HeLa Cells; Humans; Inflammation/genetics; Inflammation/immunology; Inflammation/metabolism; Interleukin-4/pharmacology; Lymphoma, Large B-Cell, Diffuse/genetics; Lymphoma, Large B-Cell, Diffuse/immunology; Lymphoma, Large B-Cell, Diffuse/metabolism; Mice; Mice, Knockout; Mutation, Missense; Phosphatidylinositol 3-Kinases/genetics; Phosphatidylinositol 3-Kinases/immunology; Phosphatidylinositol 3-Kinases/metabolism; Phosphorylation/drug effects; Protein Tyrosine Phosphatase, Non-Receptor Type 1/genetics; Protein Tyrosine Phosphatase, Non-Receptor Type 1/immunology; RNA, Messenger/biosynthesis; RNA, Messenger/genetics; RNA, Messenger/metabolism; STAT5 Transcription Factor/genetics; STAT5 Transcription Factor/immunology; STAT5 Transcription Factor/metabolism; STAT6 Transcription Factor/genetics; STAT6 Transcription Factor/immunology; Staurosporine/pharmacology; TYK2 Kinase/genetics; TYK2 Kinase/immunology; TYK2 Kinase/metabolism; Tumor Suppressor Proteins/genetics; Tumor Suppressor Proteins/immunology; Tumor Suppressor Proteins/metabolism