Bendamustine, but not fludarabine, exhibits a low stem cell toxicity in vitro.

Schmidt-Hieber, M; Busse, A; Reufi, B; Knauf, W; Thiel, E; Blau, I W

Schmidt-Hieber, M; Busse, A; Reufi, B; Knauf, W; Thiel, E; Blau, I W.

Affiliation

Schmidt-Hieber M; Medizinische Klinik III (Hämatologie, Onkologie und Transfusionsmedizin), Charité, Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany. martin.schmidt-hieber@charite.de

J Cancer Res Clin Oncol ; 135(2): 227-34, 2009 Feb.

Article in En | MEDLINE | ID: mdl-18719942

Subject(s)

Antineoplastic Agents/toxicity; Hematopoietic Stem Cells/cytology; Nitrogen Mustard Compounds/toxicity; Stem Cells/cytology; Vidarabine/analogs & derivatives; Bendamustine Hydrochloride; Blood Component Removal/methods; Bone Marrow Cells/cytology; Cell Culture Techniques/methods; Cell Survival/drug effects; Colony-Forming Units Assay; Granulocyte Colony-Stimulating Factor/pharmacology; Hematopoietic Stem Cells/drug effects; Hematopoietic Stem Cells/pathology; Humans; Models, Biological; Reference Values; Stem Cells/drug effects; Stem Cells/pathology; Vidarabine/toxicity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / Vidarabine / Hematopoietic Stem Cells / Antineoplastic Agents / Nitrogen Mustard Compounds Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Cancer Res Clin Oncol Year: 2009 Document type: Article Affiliation country: Germany Country of publication: Germany

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