Engineered modular recombinant transporters: application of new platform for targeted radiotherapeutic agents to alpha-particle emitting 211 At.

Rosenkranz, Andrey A; Vaidyanathan, Ganesan; Pozzi, Oscar R; Lunin, Vladimir G; Zalutsky, Michael R; Sobolev, Alexander S

Rosenkranz, Andrey A; Vaidyanathan, Ganesan; Pozzi, Oscar R; Lunin, Vladimir G; Zalutsky, Michael R; Sobolev, Alexander S.

Affiliation

Rosenkranz AA; Laboratory of Molecular Genetics of Intracellular Transport, Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia.

Int J Radiat Oncol Biol Phys ; 72(1): 193-200, 2008 Sep 01.

Article in En | MEDLINE | ID: mdl-18722270

Subject(s)

Astatine/therapeutic use; Cell Nucleus/radiation effects; Drug Carriers/therapeutic use; ErbB Receptors/metabolism; Alpha Particles/therapeutic use; Antigens, Polyomavirus Transforming/metabolism; Astatine/pharmacokinetics; Benzoates/pharmacokinetics; Benzoates/therapeutic use; Carcinoma, Squamous Cell/metabolism; Carcinoma, Squamous Cell/radiotherapy; Cell Line, Tumor; Cell Nucleus/metabolism; Confidence Intervals; Dihydropteridine Reductase/pharmacokinetics; Diphtheria Toxin/pharmacokinetics; Drug Carriers/pharmacokinetics; Endosomes/metabolism; Epidermal Growth Factor/metabolism; Escherichia coli Proteins/pharmacokinetics; Glioblastoma/metabolism; Glioblastoma/radiotherapy; Guanidine/analogs & derivatives; Guanidine/pharmacokinetics; Guanidine/therapeutic use; Guanidines/pharmacokinetics; Guanidines/therapeutic use; Hemeproteins/pharmacokinetics; Humans; NADH, NADPH Oxidoreductases/pharmacokinetics; Radioimmunotherapy/methods

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Carriers / Cell Nucleus / Astatine / ErbB Receptors Limits: Humans Language: En Journal: Int J Radiat Oncol Biol Phys Year: 2008 Document type: Article Affiliation country: RUSSIA Country of publication: United States

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