CD4+ T-cell decline after the interruption of antiretroviral therapy in ACTG A5170 is predicted by differential expression of genes in the ras signaling pathway.

Vahey, Maryanne T; Wang, Zhining; Su, Zhaohui; Nau, Martin E; Krambrink, Amy; Skiest, Daniel J; Margolis, David M

Vahey, Maryanne T; Wang, Zhining; Su, Zhaohui; Nau, Martin E; Krambrink, Amy; Skiest, Daniel J; Margolis, David M.

Affiliation

Vahey MT; Division of Retrovirology, The Walter Reed Army Institute of Research, Rockville, Maryland 20850, USA. mvahey@hivresearch.org

AIDS Res Hum Retroviruses ; 24(8): 1047-66, 2008 Aug.

Article in En | MEDLINE | ID: mdl-18724805

Subject(s)

Anti-Retroviral Agents/administration & dosage; HIV Infections/drug therapy; HIV Infections/genetics; Leukocytes, Mononuclear/metabolism; Signal Transduction/genetics; ras Proteins/genetics; Adult; CD4 Lymphocyte Count; Drug Administration Schedule; Female; Gene Expression Profiling; HIV/drug effects; HIV/immunology; Humans; Leukocytes, Mononuclear/virology; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Prospective Studies

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukocytes, Mononuclear / Signal Transduction / HIV Infections / Ras Proteins / Anti-Retroviral Agents Type of study: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: AIDS Res Hum Retroviruses Journal subject: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Year: 2008 Document type: Article Affiliation country: United States Country of publication: United States

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