Uptake of a recombinant human alpha-L-iduronidase (laronidase) by cultured fibroblasts and osteoblasts.

Tsukimura, Takahiro; Tajima, Youichi; Kawashima, Ikuo; Fukushige, Tomoko; Kanzaki, Tamotsu; Kanekura, Takuro; Ikekita, Masahiko; Sugawara, Kanako; Suzuki, Toshihiro; Togawa, Tadayasu; Sakuraba, Hitoshi

Tsukimura, Takahiro; Tajima, Youichi; Kawashima, Ikuo; Fukushige, Tomoko; Kanzaki, Tamotsu; Kanekura, Takuro; Ikekita, Masahiko; Sugawara, Kanako; Suzuki, Toshihiro; Togawa, Tadayasu; Sakuraba, Hitoshi.

Affiliation

Tsukimura T; Department of Clinical Genetics, The Tokyo Metropolitan Institute of Medical Science, Tokyo Metropolitan Organization for Medical Research, Bunkyo-ku, Tokyo, Japan.

Biol Pharm Bull ; 31(9): 1691-5, 2008 Sep.

Article in En | MEDLINE | ID: mdl-18758061

Subject(s)

Fibroblasts/metabolism; Iduronidase/metabolism; Osteoblasts/metabolism; Animals; Cells, Cultured; Fibroblasts/ultrastructure; Humans; Kinetics; Mice; Mucopolysaccharidosis I/metabolism; Osteoblasts/ultrastructure; Receptor, IGF Type 2/metabolism; Recombinant Proteins/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Osteoblasts / Fibroblasts / Iduronidase Limits: Animals / Humans Language: En Journal: Biol Pharm Bull Journal subject: BIOQUIMICA / FARMACOLOGIA Year: 2008 Document type: Article Affiliation country: Japan Country of publication: Japan

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