Sindbis virus vectors elicit hemagglutinin-specific humoral and cellular immune responses and offer a dose-sparing strategy for vaccination.

Miller, Annett; Center, Rob J; Stambas, John; Deliyannis, Georgia; Doherty, Peter C; Howard, Jane L; Turner, Stephen J; Purcell, Damian F J

Miller, Annett; Center, Rob J; Stambas, John; Deliyannis, Georgia; Doherty, Peter C; Howard, Jane L; Turner, Stephen J; Purcell, Damian F J.

Affiliation

Miller A; Department of Microbiology and Immunology, University of Melbourne, Parkville 3010, Australia.

Vaccine ; 26(44): 5641-8, 2008 Oct 16.

Article in En | MEDLINE | ID: mdl-18761047

Subject(s)

Genetic Vectors; Hemagglutinin Glycoproteins, Influenza Virus/immunology; Influenza A Virus, H1N1 Subtype/immunology; Influenza Vaccines/administration & dosage; Orthomyxoviridae Infections/immunology; Orthomyxoviridae Infections/prevention & control; Sindbis Virus/genetics; Animals; Antibodies, Viral/blood; Cricetinae; Female; Hemagglutinin Glycoproteins, Influenza Virus/genetics; Hemagglutinin Glycoproteins, Influenza Virus/metabolism; Immunization; Influenza A Virus, H1N1 Subtype/genetics; Lung/virology; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections/virology; Plasmids; Replicon; Sindbis Virus/immunology; T-Lymphocytes, Cytotoxic/immunology; Vaccination

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sindbis Virus / Influenza Vaccines / Orthomyxoviridae Infections / Hemagglutinin Glycoproteins, Influenza Virus / Influenza A Virus, H1N1 Subtype / Genetic Vectors Limits: Animals Language: En Journal: Vaccine Year: 2008 Document type: Article Affiliation country: Australia Country of publication: Netherlands

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