Molecular cloning and characterization of the human PED/PEA-15 gene promoter reveal antagonistic regulation by hepatocyte nuclear factor 4alpha and chicken ovalbumin upstream promoter transcription factor II.

Ungaro, Paola; Teperino, Raffaele; Mirra, Paola; Cassese, Angela; Fiory, Francesca; Perruolo, Giuseppe; Miele, Claudia; Laakso, Markku; Formisano, Pietro; Beguinot, Francesco

Ungaro, Paola; Teperino, Raffaele; Mirra, Paola; Cassese, Angela; Fiory, Francesca; Perruolo, Giuseppe; Miele, Claudia; Laakso, Markku; Formisano, Pietro; Beguinot, Francesco.

Affiliation

Ungaro P; Dipartimento di Biologia e Patologia Cellulare e Molecolare, Università di Napoli Federico II, 80131 Naples, Italy.

J Biol Chem ; 283(45): 30970-9, 2008 Nov 07.

Article in En | MEDLINE | ID: mdl-18765665

Subject(s)

COUP Transcription Factor II/metabolism; Glucose/metabolism; Hepatocyte Nuclear Factor 4/metabolism; Lipid Metabolism/physiology; Phosphoproteins/biosynthesis; Response Elements/physiology; Transcription, Genetic/physiology; Animals; Apoptosis Regulatory Proteins; COUP Transcription Factor II/genetics; Cloning, Molecular; Diabetes Mellitus, Type 2/genetics; Diabetes Mellitus, Type 2/metabolism; Glucose/genetics; HeLa Cells; Hepatocyte Nuclear Factor 4/genetics; Humans; Intracellular Signaling Peptides and Proteins/genetics; Liver/metabolism; Mice; Mice, Transgenic; Phosphoproteins/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphoproteins / Transcription, Genetic / Response Elements / COUP Transcription Factor II / Hepatocyte Nuclear Factor 4 / Lipid Metabolism / Glucose Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2008 Document type: Article Affiliation country: Italy

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