Downregulation of the hexokinase II gene sensitizes human colon cancer cells to 5-fluorouracil.

Peng, Qiu-Ping; Zhou, Jin-Ming; Zhou, Qi; Pan, Feng; Zhong, Da-Ping; Liang, Hou-Jie

Peng, Qiu-Ping; Zhou, Jin-Ming; Zhou, Qi; Pan, Feng; Zhong, Da-Ping; Liang, Hou-Jie.

Affiliation

Peng QP; Department of Oncology, Southwest Hospital, Third Military Medical University, Chongqing, China.

Chemotherapy ; 54(5): 357-63, 2008.

Article in En | MEDLINE | ID: mdl-18772588

Subject(s)

Colonic Neoplasms/enzymology; Colonic Neoplasms/pathology; Down-Regulation; Fluorouracil/pharmacology; Gene Expression Regulation, Neoplastic; Hexokinase/genetics; Hexokinase/metabolism; Apoptosis/drug effects; Caspase 3/metabolism; Cell Line, Tumor; Colonic Neoplasms/drug therapy; Enzyme Activation/drug effects; Humans; Matrix Metalloproteinases/metabolism; RNA Interference

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Down-Regulation / Gene Expression Regulation, Neoplastic / Colonic Neoplasms / Fluorouracil / Hexokinase Limits: Humans Language: En Journal: Chemotherapy Year: 2008 Document type: Article Affiliation country: China Country of publication: Switzerland

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