Bortezomib-induced enzyme-targeted radiation therapy in herpesvirus-associated tumors.

Fu, De-Xue; Tanhehco, Yvette; Chen, Jianmeng; Foss, Catherine A; Fox, James J; Chong, Ja-Mun; Hobbs, Robert F; Fukayama, Masashi; Sgouros, George; Kowalski, Jeanne; Pomper, Martin G; Ambinder, Richard F

Fu, De-Xue; Tanhehco, Yvette; Chen, Jianmeng; Foss, Catherine A; Fox, James J; Chong, Ja-Mun; Hobbs, Robert F; Fukayama, Masashi; Sgouros, George; Kowalski, Jeanne; Pomper, Martin G; Ambinder, Richard F.

Affiliation

Fu DX; Department of Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA.

Nat Med ; 14(10): 1118-22, 2008 Oct.

Article in En | MEDLINE | ID: mdl-18776891

Subject(s)

Antineoplastic Agents/pharmacology; Arabinofuranosyluracil/analogs & derivatives; Boronic Acids/pharmacology; Burkitt Lymphoma/radiotherapy; Iodine Radioisotopes/therapeutic use; Pyrazines/pharmacology; Radiopharmaceuticals/therapeutic use; Stomach Neoplasms/radiotherapy; Thymidine Kinase/metabolism; Animals; Arabinofuranosyluracil/therapeutic use; Bortezomib; Cell Line, Tumor; Herpesviridae Infections/radiotherapy; Herpesvirus 4, Human/enzymology; Humans; Male; Mice; Mice, SCID; Sarcoma, Kaposi/radiotherapy; Thymidine Kinase/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arabinofuranosyluracil / Pyrazines / Stomach Neoplasms / Thymidine Kinase / Boronic Acids / Burkitt Lymphoma / Radiopharmaceuticals / Iodine Radioisotopes / Antineoplastic Agents Type of study: Risk_factors_studies Limits: Animals / Humans / Male Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2008 Document type: Article Affiliation country: United States

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