Soluble and insoluble nickel compounds exert a differential inhibitory effect on cell growth through IKKalpha-dependent cyclin D1 down-regulation.

Ouyang, Weiming; Zhang, Dongyun; Li, Jingxia; Verma, Udit N; Costa, Max; Huang, Chuanshu

Ouyang, Weiming; Zhang, Dongyun; Li, Jingxia; Verma, Udit N; Costa, Max; Huang, Chuanshu.

Affiliation

Ouyang W; Nelson Institute of Environmental Medicine, New York University School of Medicine, Tuxedo, New York, USA.

J Cell Physiol ; 218(1): 205-14, 2009 Jan.

Article in En | MEDLINE | ID: mdl-18792914

Subject(s)

Cell Proliferation/drug effects; Cyclin D1/metabolism; I-kappa B Kinase/metabolism; Nickel/toxicity; Animals; Base Sequence; Carcinogens/toxicity; Cell Cycle/drug effects; Cell Line; Cells, Cultured; Cyclin D1/genetics; DNA Primers/genetics; Down-Regulation/drug effects; Humans; Hypoxia-Inducible Factor 1, alpha Subunit/deficiency; Hypoxia-Inducible Factor 1, alpha Subunit/genetics; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism; I-kappa B Kinase/deficiency; I-kappa B Kinase/genetics; Mice; Mice, Knockout; RNA, Messenger/genetics; RNA, Messenger/metabolism; Solubility

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cyclin D1 / Cell Proliferation / I-kappa B Kinase / Nickel Limits: Animals / Humans Language: En Journal: J Cell Physiol Year: 2009 Document type: Article Affiliation country: United States Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google