Asymmetry in the lipid affinity of bihelical amphipathic peptides. A structural determinant for the specificity of ABCA1-dependent cholesterol efflux by peptides.

Sethi, Amar A; Stonik, John A; Thomas, Fairwell; Demosky, Steve J; Amar, Marcelo; Neufeld, Edward; Brewer, H Bryan; Davidson, W Sean; D'Souza, Wilissa; Sviridov, Dmitri; Remaley, Alan T

Sethi, Amar A; Stonik, John A; Thomas, Fairwell; Demosky, Steve J; Amar, Marcelo; Neufeld, Edward; Brewer, H Bryan; Davidson, W Sean; D'Souza, Wilissa; Sviridov, Dmitri; Remaley, Alan T.

Affiliation

Sethi AA; Lipoprotein Metabolism Section, Pulmonary and Vascular Medicine Branch, NHLBI, National Institutes of Health, Bethesda, Maryland 20892-1508, USA.

J Biol Chem ; 283(47): 32273-82, 2008 Nov 21.

Article in En | MEDLINE | ID: mdl-18805791

Subject(s)

ATP-Binding Cassette Transporters/chemistry; Cholesterol/metabolism; Lipids/chemistry; ATP Binding Cassette Transporter 1; Alanine/chemistry; Amino Acid Sequence; Biological Transport; Circular Dichroism; Erythrocytes/cytology; Guanidine/chemistry; Humans; Molecular Sequence Data; Peptides/chemistry; Phospholipids/chemistry; Protein Conformation; Time Factors

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cholesterol / ATP-Binding Cassette Transporters / Lipids Limits: Humans Language: En Journal: J Biol Chem Year: 2008 Document type: Article Affiliation country: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google