G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription.

Tachibana, Makoto; Matsumura, Yasuko; Fukuda, Mikiko; Kimura, Hiroshi; Shinkai, Yoichi

Tachibana, Makoto; Matsumura, Yasuko; Fukuda, Mikiko; Kimura, Hiroshi; Shinkai, Yoichi.

Affiliation

Tachibana M; Experimental Research Center for Infectious Diseases, Institute for Virus Research, Kyoto University, Sakyo-ku, Kyoto, Japan. mtachiba@virus.kyoto-u.ac.jp

EMBO J ; 27(20): 2681-90, 2008 Oct 22.

Article in En | MEDLINE | ID: mdl-18818694

Subject(s)

DNA Methylation; Gene Expression Regulation; Gene Silencing; Histone-Lysine N-Methyltransferase/physiology; Histones/chemistry; Transcription, Genetic; Animals; Catalysis; CpG Islands; Embryonic Stem Cells/metabolism; Histone-Lysine N-Methyltransferase/metabolism; Mice; Mice, Knockout; Models, Biological; Mutation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / Histones / Gene Expression Regulation / Histone-Lysine N-Methyltransferase / DNA Methylation / Gene Silencing Limits: Animals Language: En Journal: EMBO J Year: 2008 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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