Methylated bismuth, but not bismuth citrate or bismuth glutathione, induces cyto- and genotoxic effects in human cells in vitro.

von Recklinghausen, U; Hartmann, L M; Rabieh, S; Hippler, J; Hirner, A V; Rettenmeier, A W; Dopp, E

von Recklinghausen, U; Hartmann, L M; Rabieh, S; Hippler, J; Hirner, A V; Rettenmeier, A W; Dopp, E.

Affiliation

von Recklinghausen U; Institute of Hygiene and Occupational Health, University Hospital, Hufelandstrasse 55, 45122 Essen, Germany.

Chem Res Toxicol ; 21(6): 1219-28, 2008 Jun.

Article in En | MEDLINE | ID: mdl-18826176

Subject(s)

Bismuth/chemistry; Bismuth/toxicity; Cytotoxins/toxicity; DNA Damage/drug effects; Mutagens/toxicity; Bismuth/metabolism; Cell Survival/drug effects; Cells, Cultured; Chromatography, Gas; Chromosome Aberrations/chemically induced; Citrates/chemistry; Erythrocytes/metabolism; Glutathione/chemistry; Hepatocytes/drug effects; Hepatocytes/metabolism; Humans; Lymphocytes/metabolism; Methylation; Molecular Structure; Mutagens/chemistry; Mutagens/metabolism; Reactive Oxygen Species/metabolism; Sister Chromatid Exchange/drug effects; Sister Chromatid Exchange/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bismuth / DNA Damage / Cytotoxins / Mutagens Limits: Humans Language: En Journal: Chem Res Toxicol Journal subject: TOXICOLOGIA Year: 2008 Document type: Article Affiliation country: Germany Country of publication: United States

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