HBV A1762T, G1764A mutations are a valuable biomarker for identifying a subset of male HBsAg carriers at extremely high risk of hepatocellular carcinoma: a prospective study.

Fang, Zhong-Liao; Sabin, Caroline A; Dong, Bai-Qing; Ge, Lian-Ying; Wei, Shao-Chao; Chen, Qin-Yan; Fang, Kong-Xiong; Yang, Jin-Ye; Wang, Xue-Yan; Harrison, Tim J

Fang, Zhong-Liao; Sabin, Caroline A; Dong, Bai-Qing; Ge, Lian-Ying; Wei, Shao-Chao; Chen, Qin-Yan; Fang, Kong-Xiong; Yang, Jin-Ye; Wang, Xue-Yan; Harrison, Tim J.

Affiliation

Fang ZL; Department of Medicine, Royal Free and University College Medical School, University College London, London, United Kingdom.

Am J Gastroenterol ; 103(9): 2254-62, 2008 Sep.

Article in En | MEDLINE | ID: mdl-18844615

Subject(s)

Carcinoma, Hepatocellular/genetics; Carcinoma, Hepatocellular/virology; Hepatitis B Surface Antigens/genetics; Hepatitis B virus/genetics; Liver Neoplasms/genetics; Liver Neoplasms/virology; Adult; Biomarkers, Tumor/genetics; Biomarkers, Tumor/immunology; Carcinoma, Hepatocellular/epidemiology; Carcinoma, Hepatocellular/immunology; Chi-Square Distribution; China/epidemiology; Hepatitis B Surface Antigens/immunology; Humans; Liver Neoplasms/epidemiology; Liver Neoplasms/immunology; Male; Middle Aged; Mutation; Poisson Distribution; Polymerase Chain Reaction; Prospective Studies; Risk Factors; Rural Population

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatitis B virus / Carcinoma, Hepatocellular / Hepatitis B Surface Antigens / Liver Neoplasms Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Am J Gastroenterol Year: 2008 Document type: Article Affiliation country: United kingdom

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