Induced hypotension in orthognathic surgery: a comparative study of 2 pharmacological protocols.
J Oral Maxillofac Surg
; 66(11): 2261-9, 2008 Nov.
Article
in En
| MEDLINE
| ID: mdl-18940490
ABSTRACT
PURPOSE:
The objective of this comparative study was to report on the use of 2 different pharmaceutical protocols involving 2 different anesthetic techniques (IV and balanced) to induce hypotension in patients submitted to orthognathic surgery by assessing the patients' intra- and postoperative physiologic response and hemodynamic stability. PATIENTS ANDMETHODS:
Twenty ASA I patients, between 17 and 44 years of age who had dental and skeletal deformities were subdivided into 2 groups group I (clonidine associated to remifentanil), and group II (dexmedetomidine associated to isoflurane), in addition, other drugs were common to both groups. The following responses were assessed arterial blood pressure, heart rate, temperature during intra- and postoperative periods, incidence of nausea and vomiting, postoperative pain, awakening time, extubation time, and postanesthetic recovery time.RESULTS:
The results of the study using Repeated Measures Test statistical analysis showed that there were no significant differences between the 2 groups in respect to physiologic responses or surgery time.CONCLUSION:
Both protocols tried in this study proved to be effective and safe, and they seem to be interesting alternatives in longer orthognathic surgeries with the expectation of an important blood loss. The choice for either protocol should be based on the inherent risks involved in their use and their cost-benefit ratio.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Oral Surgical Procedures
/
Hypotension, Controlled
/
Anesthesia, Dental
Type of study:
Clinical_trials
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
J Oral Maxillofac Surg
Year:
2008
Document type:
Article
Affiliation country:
Brazil