The effects of trichostatin A on the oncolytic ability of herpes simplex virus for oral squamous cell carcinoma cells.

Katsura, T; Iwai, S; Ota, Y; Shimizu, H; Ikuta, K; Yura, Y

Katsura, T; Iwai, S; Ota, Y; Shimizu, H; Ikuta, K; Yura, Y.

Affiliation

Katsura T; Department of Oral and Maxillofacial Surgery, Osaka University Graduate School of Dentistry, Osaka University, Suita, Osaka, Japan.

Cancer Gene Ther ; 16(3): 237-45, 2009 Mar.

Article in En | MEDLINE | ID: mdl-18949013

Subject(s)

Carcinoma, Squamous Cell/pathology; Enzyme Inhibitors/pharmacology; Herpesvirus 1, Human/drug effects; Hydroxamic Acids/pharmacology; Mouth Neoplasms/pathology; Oncolytic Virotherapy; Virus Activation/drug effects; Acetylation/drug effects; Cell Line, Tumor/enzymology; Cell Line, Tumor/virology; Defective Viruses/drug effects; Defective Viruses/genetics; Defective Viruses/physiology; Drug Screening Assays, Antitumor; Gene Expression Regulation, Viral/drug effects; Herpesvirus 1, Human/genetics; Herpesvirus 1, Human/physiology; Histone Deacetylase Inhibitors; Histones/metabolism; Humans; NF-kappa B/metabolism; Neoplasm Proteins/antagonists & inhibitors; Neoplasm Proteins/metabolism; Peptides/pharmacology; Protein Processing, Post-Translational/drug effects; Protein Transport/drug effects; Transcription Factor RelA/physiology; Viral Proteins/genetics; Virus Replication/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Virus Activation / Mouth Neoplasms / Carcinoma, Squamous Cell / Herpesvirus 1, Human / Enzyme Inhibitors / Oncolytic Virotherapy / Hydroxamic Acids Limits: Humans Language: En Journal: Cancer Gene Ther Journal subject: GENETICA MEDICA / NEOPLASIAS / TERAPEUTICA Year: 2009 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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