The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAP.

Striedinger, Katherine; VandenBerg, Scott R; Baia, Gilson S; McDermott, Michael W; Gutmann, David H; Lal, Anita

Striedinger, Katherine; VandenBerg, Scott R; Baia, Gilson S; McDermott, Michael W; Gutmann, David H; Lal, Anita.

Affiliation

Striedinger K; Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, CA 94143, USA.

Neoplasia ; 10(11): 1204-12, 2008 Nov.

Article in En | MEDLINE | ID: mdl-18953429

Subject(s)

Meningioma/metabolism; Neurofibromin 2/metabolism; Nuclear Proteins/metabolism; Signal Transduction; Transcription Factors/metabolism; Arachnoid/cytology; Arachnoid/metabolism; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Proliferation; Cloning, Molecular; Cyclin E/metabolism; Genes, Neurofibromatosis 2; Humans; Meningioma/genetics; Meningioma/pathology; Neurofibromin 2/genetics; Nuclear Proteins/genetics; Oncogene Proteins/metabolism; Polymerase Chain Reaction; RNA Interference; Transcription Factors/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Nuclear Proteins / Signal Transduction / Neurofibromin 2 / Meningioma Limits: Humans Language: En Journal: Neoplasia Journal subject: NEOPLASIAS Year: 2008 Document type: Article Affiliation country: United States Country of publication: United States

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