Population pharmacokinetics and pharmacogenetics of imatinib in children and adults.

Petain, Aurélie; Kattygnarath, Darouna; Azard, Julie; Chatelut, Etienne; Delbaldo, Catherine; Geoerger, Birgit; Barrois, Michel; Séronie-Vivien, Sophie; LeCesne, Axel; Vassal, Gilles

Petain, Aurélie; Kattygnarath, Darouna; Azard, Julie; Chatelut, Etienne; Delbaldo, Catherine; Geoerger, Birgit; Barrois, Michel; Séronie-Vivien, Sophie; LeCesne, Axel; Vassal, Gilles.

Affiliation

Petain A; EA3035, Institut Claudius-Regaud, Université Paul-Sabatier, Toulouse, France.

Clin Cancer Res ; 14(21): 7102-9, 2008 Nov 01.

Article in En | MEDLINE | ID: mdl-18981009

Subject(s)

Gastrointestinal Stromal Tumors/genetics; Gastrointestinal Stromal Tumors/metabolism; Piperazines/pharmacology; Piperazines/pharmacokinetics; Pyrimidines/pharmacology; Pyrimidines/pharmacokinetics; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Benzamides; Blood Proteins/metabolism; Body Weight; Child; Child, Preschool; Glycoproteins/blood; Humans; Imatinib Mesylate; Metabolic Clearance Rate/genetics; Middle Aged; Pharmacogenetics; Piperazines/metabolism; Polymorphism, Genetic; Population Groups; Pyrimidines/metabolism; Serum Albumin; Sex Factors; Young Adult

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Pyrimidines / Gastrointestinal Stromal Tumors Type of study: Prognostic_studies Limits: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Humans / Middle aged Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2008 Document type: Article Affiliation country: France

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google