Urea-dependent unfolding of HIV-1 protease studied by circular dichroism and small-angle X-ray scattering.

Kogo, Hiroyuki; Takeuchi, Kayoko; Inoue, Hideshi; Kihara, Hiroshi; Kojima, Masaki; Takahashi, Kenji

Kogo, Hiroyuki; Takeuchi, Kayoko; Inoue, Hideshi; Kihara, Hiroshi; Kojima, Masaki; Takahashi, Kenji.

Affiliation

Kogo H; School of Life Science, Tokyo University of Pharmacy and Life Sciences, Horinouchi, Hachioji, Tokyo 192-0392, Japan.

Biochim Biophys Acta ; 1794(1): 70-4, 2009 Jan.

Article in En | MEDLINE | ID: mdl-18992856

Subject(s)

HIV Protease/chemistry; Protein Folding/drug effects; Urea/pharmacology; Circular Dichroism; HIV Protease/metabolism; Pepsin A/chemistry; Pepsin A/metabolism; Protein Denaturation/drug effects; Protein Structure, Secondary/drug effects; Scattering, Small Angle; Urea/chemistry; X-Ray Diffraction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urea / HIV Protease / Protein Folding Language: En Journal: Biochim Biophys Acta Year: 2009 Document type: Article Affiliation country: Japan Country of publication: Netherlands

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