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Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4.
Cortellino, Salvatore; Wang, Chengbing; Wang, Baolin; Bassi, Maria Rosaria; Caretti, Elena; Champeval, Delphine; Calmont, Amelie; Jarnik, Michal; Burch, John; Zaret, Kenneth S; Larue, Lionel; Bellacosa, Alfonso.
Affiliation
  • Cortellino S; Human Genetics Program, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Dev Biol ; 325(1): 225-37, 2009 Jan 01.
Article in En | MEDLINE | ID: mdl-19000668
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cilia / Gene Silencing / Intracellular Signaling Peptides and Proteins / DNA Repair / Embryo Loss / Endodeoxyribonucleases / Hedgehog Proteins Limits: Animals Language: En Journal: Dev Biol Year: 2009 Document type: Article Affiliation country: United States Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cilia / Gene Silencing / Intracellular Signaling Peptides and Proteins / DNA Repair / Embryo Loss / Endodeoxyribonucleases / Hedgehog Proteins Limits: Animals Language: En Journal: Dev Biol Year: 2009 Document type: Article Affiliation country: United States Country of publication: United States