Bacillus anthracis peptidoglycan stimulates an inflammatory response in monocytes through the p38 mitogen-activated protein kinase pathway.

Langer, Marybeth; Malykhin, Alexander; Maeda, Kenichiro; Chakrabarty, Kaushik; Williamson, Kelly S; Feasley, Christa L; West, Christopher M; Metcalf, Jordan P; Coggeshall, K Mark

Langer, Marybeth; Malykhin, Alexander; Maeda, Kenichiro; Chakrabarty, Kaushik; Williamson, Kelly S; Feasley, Christa L; West, Christopher M; Metcalf, Jordan P; Coggeshall, K Mark.

Affiliation

Langer M; Immunobiology and Cancer Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.

PLoS One ; 3(11): e3706, 2008.

Article in En | MEDLINE | ID: mdl-19002259

Subject(s)

Bacillus anthracis/metabolism; Inflammation Mediators/metabolism; MAP Kinase Signaling System; Monocytes/immunology; Peptidoglycan/pharmacology; p38 Mitogen-Activated Protein Kinases/metabolism; Bacillus anthracis/immunology; DNA, Bacterial/metabolism; Humans; Leukocytes, Mononuclear/immunology; Monocytes/enzymology; Neutrophils/immunology; Neutrophils/metabolism; Peptidoglycan/immunology; RNA, Bacterial/metabolism; RNA, Messenger/metabolism; Tumor Necrosis Factor-alpha/genetics; Tumor Necrosis Factor-alpha/immunology; Tumor Necrosis Factor-alpha/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacillus anthracis / Monocytes / Peptidoglycan / Inflammation Mediators / MAP Kinase Signaling System / P38 Mitogen-Activated Protein Kinases Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2008 Document type: Article Affiliation country: United States Country of publication: United States

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