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Four new biflavonoids from Selaginella uncinata and their anti-anoxic effect.
Zheng, Jun-Xia; Wang, Nai-Li; Liu, Hong-Wei; Chen, Hai-Feng; Li, Ming-Ming; Wu, Li-Ying; Fan, Ming; Yao, Xin-Sheng.
Affiliation
  • Zheng JX; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
J Asian Nat Prod Res ; 10(9-10): 945-52, 2008.
Article in En | MEDLINE | ID: mdl-19003613
ABSTRACT
The 60% ethanolic extract of Selaginella uncinata (Desv.) Spring possessed potent anti-anoxic effect in the anoxic PC12 cell assay. A phytochemical study of its EtOAc-soluble part led to the isolation of four new and three known biflavonoids. Their structures were established on the basis of physico-chemical properties and spectroscopic analysis. The absolute configurations of the new compounds were determined with the aid of circular dichroism (CD) spectroscopy. Compounds 4 and 5 showed potent anti-anoxic effect in the anoxic PC12 cell assay.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Flavonoids / Selaginellaceae Limits: Animals Language: En Journal: J Asian Nat Prod Res Journal subject: BOTANICA / QUIMICA Year: 2008 Document type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Flavonoids / Selaginellaceae Limits: Animals Language: En Journal: J Asian Nat Prod Res Journal subject: BOTANICA / QUIMICA Year: 2008 Document type: Article Affiliation country: China