The role of reduced pterins in resistance to reactive oxygen and nitrogen intermediates in the protozoan parasite Leishmania.

Moreira, Wilfried; Leblanc, Eric; Ouellette, Marc

Moreira, Wilfried; Leblanc, Eric; Ouellette, Marc.

Affiliation

Moreira W; Centre de Recherche en Infectiologie du CHUL, Université Laval, Québec, QC G1V 4G2, Canada.

Free Radic Biol Med ; 46(3): 367-75, 2009 Feb 01.

Article in En | MEDLINE | ID: mdl-19022374

Subject(s)

Leishmania/enzymology; Macrophages/enzymology; Nitric Oxide/metabolism; Oxidoreductases/metabolism; Protozoan Proteins/metabolism; Pterins/metabolism; Animals; Cell Line; Cells, Cultured; Gene Knockdown Techniques; Humans; Hydrogen Peroxide/metabolism; Leishmania/genetics; Leishmania/pathogenicity; Leishmaniasis/enzymology; Leishmaniasis/genetics; Macrophages/parasitology; Mice; Nitric Oxide/genetics; Oxidative Stress/genetics; Oxidoreductases/genetics; Protozoan Proteins/genetics; Species Specificity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidoreductases / Pterins / Protozoan Proteins / Leishmania / Macrophages / Nitric Oxide Limits: Animals / Humans Language: En Journal: Free Radic Biol Med Journal subject: BIOQUIMICA / MEDICINA Year: 2009 Document type: Article Affiliation country: Canada Country of publication: United States

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