Identification and structural mechanism for a novel interaction between a ubiquitin ligase WWP1 and Nogo-A, a key inhibitor for central nervous system regeneration.

Qin, Haina; Pu, Helen X; Li, Minfen; Ahmed, Sohail; Song, Jianxing

Qin, Haina; Pu, Helen X; Li, Minfen; Ahmed, Sohail; Song, Jianxing.

Affiliation

Qin H; Department of Biological Sciences, Faculty of Science, National University of Singapore, Singapore.

Biochemistry ; 47(51): 13647-58, 2008 Dec 23.

Article in En | MEDLINE | ID: mdl-19035836

Subject(s)

Central Nervous System/metabolism; Myelin Proteins/chemistry; Ubiquitin-Protein Ligases/chemistry; Amino Acid Sequence; Animals; Circular Dichroism; Glutathione Transferase/metabolism; Humans; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Sequence Data; Myelin Proteins/metabolism; Nogo Proteins; Protein Binding; Sequence Homology, Amino Acid; Ubiquitin/chemistry; Ubiquitin-Protein Ligases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Central Nervous System / Ubiquitin-Protein Ligases / Myelin Proteins Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Biochemistry Year: 2008 Document type: Article Affiliation country: Singapore Country of publication: United States

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