Facile synthesis of bis(4,5-dihydro-1H-pyrazole-1-carboxamides) and their thio-analogues of potential PGE(2) inhibitory properties.

Barsoum, Flora F; Girgis, Adel S

Barsoum, Flora F; Girgis, Adel S.

Affiliation

Barsoum FF; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt.

Eur J Med Chem ; 44(5): 2172-7, 2009 May.

Article in En | MEDLINE | ID: mdl-19056146

Subject(s)

Dinoprostone/antagonists & inhibitors; Pyrazoles/chemical synthesis; Amides; Animals; Anti-Inflammatory Agents/chemical synthesis; Anti-Inflammatory Agents/pharmacology; Drug Evaluation, Preclinical; Edema/drug therapy; Pyrazoles/pharmacology; Rats; Semicarbazides; Structure-Activity Relationship

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Dinoprostone Limits: Animals Language: En Journal: Eur J Med Chem Year: 2009 Document type: Article Affiliation country: Egypt Country of publication: France

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