Cordycepin inhibits IL-1beta-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts.

Noh, E-M; Kim, J-S; Hur, H; Park, B-H; Song, E-K; Han, M-K; Kwon, K-B; Yoo, W-H; Shim, I-K; Lee, S J; Youn, H J; Lee, Y-R

Noh, E-M; Kim, J-S; Hur, H; Park, B-H; Song, E-K; Han, M-K; Kwon, K-B; Yoo, W-H; Shim, I-K; Lee, S J; Youn, H J; Lee, Y-R.

Affiliation

Noh EM; Department of Biochemistry, Institute for Medical Science, Chonbuk National University Medical School, Jeonju, South Korea.

Rheumatology (Oxford) ; 48(1): 45-8, 2009 Jan.

Article in En | MEDLINE | ID: mdl-19056796

Subject(s)

Antirheumatic Agents/pharmacology; Arthritis, Rheumatoid/enzymology; Deoxyadenosines/pharmacology; Interleukin-1beta/antagonists & inhibitors; Matrix Metalloproteinase 1/biosynthesis; Matrix Metalloproteinase 3/biosynthesis; Arthritis, Rheumatoid/immunology; Arthritis, Rheumatoid/pathology; Cell Survival/drug effects; Cells, Cultured; Chemokines/biosynthesis; DNA-Binding Proteins/metabolism; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical/methods; Fibroblasts/drug effects; Fibroblasts/enzymology; Fibroblasts/pathology; Gene Expression Regulation, Enzymologic/drug effects; Humans; Interleukin-1beta/pharmacology; MAP Kinase Signaling System/drug effects; Matrix Metalloproteinase 1/genetics; Matrix Metalloproteinase 3/genetics; NF-kappa B/metabolism; Synovial Membrane/drug effects; Synovial Membrane/enzymology; Synovial Membrane/pathology; Transcription Factor AP-1/metabolism; Up-Regulation/drug effects

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Deoxyadenosines / Antirheumatic Agents / Matrix Metalloproteinase 3 / Matrix Metalloproteinase 1 / Interleukin-1beta Limits: Humans Language: En Journal: Rheumatology (Oxford) Journal subject: REUMATOLOGIA Year: 2009 Document type: Article Affiliation country: South Korea

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google