Conserved sequence in the aggrecan interglobular domain modulates cleavage by ADAMTS-4 and ADAMTS-5.

Miwa, Hazuki E; Gerken, Thomas A; Huynh, Tru D; Duesler, Lori R; Cotter, Meghan; Hering, Thomas M

Miwa, Hazuki E; Gerken, Thomas A; Huynh, Tru D; Duesler, Lori R; Cotter, Meghan; Hering, Thomas M.

Affiliation

Miwa HE; Department of Biochemistry, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA.

Biochim Biophys Acta ; 1790(3): 161-72, 2009 Mar.

Article in En | MEDLINE | ID: mdl-19101611

Subject(s)

ADAM Proteins/metabolism; Aggrecans/chemistry; Conserved Sequence; Procollagen N-Endopeptidase/metabolism; ADAM Proteins/genetics; ADAMTS4 Protein; ADAMTS5 Protein; Aggrecans/metabolism; Animals; Blotting, Western; Cattle; Glycosylation; Hydrolysis; Mutagenesis, Site-Directed; Procollagen N-Endopeptidase/genetics; Substrate Specificity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Procollagen N-Endopeptidase / Conserved Sequence / ADAM Proteins / Aggrecans Limits: Animals Language: En Journal: Biochim Biophys Acta Year: 2009 Document type: Article Affiliation country: United States

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