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IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors.
Bleeker, Fonnet E; Lamba, Simona; Leenstra, Sieger; Troost, Dirk; Hulsebos, Theo; Vandertop, W Peter; Frattini, Milo; Molinari, Francesca; Knowles, Margaret; Cerrato, Aniello; Rodolfo, Monica; Scarpa, Aldo; Felicioni, Lara; Buttitta, Fiamma; Malatesta, Sara; Marchetti, Antonio; Bardelli, Alberto.
Affiliation
  • Bleeker FE; Neurosurgical Center Amsterdam, Location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Hum Mutat ; 30(1): 7-11, 2009 Jan.
Article in En | MEDLINE | ID: mdl-19117336
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glioblastoma / Glioma / Isocitrate Dehydrogenase / Mutation Limits: Humans Language: En Journal: Hum Mutat Journal subject: GENETICA MEDICA Year: 2009 Document type: Article Affiliation country: Netherlands Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glioblastoma / Glioma / Isocitrate Dehydrogenase / Mutation Limits: Humans Language: En Journal: Hum Mutat Journal subject: GENETICA MEDICA Year: 2009 Document type: Article Affiliation country: Netherlands Country of publication: United States