Efficacy of high-flow dialysate continuous hemodiafiltration in the treatment of fulminant hepatic failure.
Transfus Apher Sci
; 40(1): 61-70, 2009 Feb.
Article
in En
| MEDLINE
| ID: mdl-19117803
ABSTRACT
We compared the clinical efficacy of high-flow dialysate continuous hemodiafiltration (HFCHDF) performed as artificial liver support (ALS) in fulminant hepatic failure (FHF) with those of conventional ALS techniques. Ninety patients were divided into non-HFCHDF and HFCHDF groups. Rate of recovery from coma was significantly higher in the HFCHDF group (70.2%) than in the non-HFCHDF group (44.2%) (p<0.01). The excellent recovery rate from coma achieved in patients with FHF by HFCHDF may be due to its enhanced capacity for liver support enabling efficient removal of substances causing hepatic coma from blood. HFCHDF should thus be useful for ALS.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Liver Failure, Acute
/
Hemodiafiltration
Type of study:
Observational_studies
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Transfus Apher Sci
Journal subject:
HEMATOLOGIA
Year:
2009
Document type:
Article
Affiliation country:
Japan