Glomerulosclerosis, Focal Segmental/metabolism; Mutation; NFATC Transcription Factors/metabolism; Podocytes/metabolism; TRPC Cation Channels/metabolism; Transcription, Genetic; Benzylamines/pharmacology; Calcineurin/metabolism; Calcineurin Inhibitors; Calcium/metabolism; Calcium-Calmodulin-Dependent Protein Kinase Type 2/antagonists & inhibitors; Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism; Cell Line; Cell Membrane/metabolism; Chromones/pharmacology; Cyclosporine/pharmacology; Enzyme Inhibitors/pharmacology; Glomerulosclerosis, Focal Segmental/genetics; Glycosylation; Humans; Membrane Potentials; Morpholines/pharmacology; Phosphatidylinositol 3-Kinases/metabolism; Phosphoinositide-3 Kinase Inhibitors; Podocytes/drug effects; Podocytes/enzymology; Protein Processing, Post-Translational; RNA, Messenger/metabolism; Receptor, Muscarinic M1/metabolism; Signal Transduction; Sulfonamides/pharmacology; TRPC Cation Channels/genetics; TRPC6 Cation Channel; Transcription, Genetic/drug effects; Transfection