Predicting circulating human metabolites: how good are we?

Anderson, Shelby; Luffer-Atlas, Debra; Knadler, Mary Pat

Anderson, Shelby; Luffer-Atlas, Debra; Knadler, Mary Pat.

Affiliation

Anderson S; Department of Drug Disposition, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, USA.

Chem Res Toxicol ; 22(2): 243-56, 2009 Feb.

Article in En | MEDLINE | ID: mdl-19138063

Subject(s)

Drug Evaluation, Preclinical/methods; Pharmaceutical Preparations/metabolism; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Guidelines as Topic; Humans; Mass Spectrometry; Metabolic Networks and Pathways; Models, Animal; Pharmaceutical Preparations/blood; Predictive Value of Tests

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Drug Evaluation, Preclinical Type of study: Guideline / Prognostic_studies / Qualitative_research / Risk_factors_studies Limits: Humans Language: En Journal: Chem Res Toxicol Journal subject: TOXICOLOGIA Year: 2009 Document type: Article Affiliation country: United States Country of publication: United States

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