Estrogen signals via an extra-nuclear pathway involving IGF-1R and EGFR in tamoxifen-sensitive and -resistant breast cancer cells.

Santen, Richard J; Fan, Ping; Zhang, Zhenguo; Bao, Yongde; Song, Robert X-D; Yue, Wei

Santen, Richard J; Fan, Ping; Zhang, Zhenguo; Bao, Yongde; Song, Robert X-D; Yue, Wei.

Affiliation

Santen RJ; Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, VA 22908, United States. rjs5y@virginia.edu

Steroids ; 74(7): 586-94, 2009 Jul.

Article in En | MEDLINE | ID: mdl-19138696

Subject(s)

Antineoplastic Agents, Hormonal/pharmacology; Breast Neoplasms/drug therapy; Cell Nucleus/metabolism; Drug Resistance, Neoplasm; ErbB Receptors/metabolism; Estrogens/metabolism; Receptor, IGF Type 1/metabolism; Tamoxifen/pharmacology; Apoptosis; Breast Neoplasms/metabolism; Breast Neoplasms/pathology; Estrogen Receptor alpha/metabolism; Humans; Signal Transduction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tamoxifen / Breast Neoplasms / Cell Nucleus / Receptor, IGF Type 1 / Drug Resistance, Neoplasm / Antineoplastic Agents, Hormonal / Estrogens / ErbB Receptors Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Steroids Year: 2009 Document type: Article Affiliation country: United States Country of publication: United States

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