Synthesis of apoptosis-inducing iminophosphorane organogold(III) complexes and study of their interactions with biomolecular targets.

Shaik, Neha; Martínez, Alberto; Augustin, Idline; Giovinazzo, Hugh; Varela-Ramírez, Armando; Sanaú, Mercedes; Aguilera, Renato J; Contel, María

Shaik, Neha; Martínez, Alberto; Augustin, Idline; Giovinazzo, Hugh; Varela-Ramírez, Armando; Sanaú, Mercedes; Aguilera, Renato J; Contel, María.

Affiliation

Shaik N; Department of Chemistry, Brooklyn College and The Graduate Center, The City University of New York, Brooklyn, New York 11210, USA.

Inorg Chem ; 48(4): 1577-87, 2009 Feb 16.

Article in En | MEDLINE | ID: mdl-19146434

Subject(s)

Antineoplastic Agents/chemical synthesis; Apoptosis/drug effects; Organogold Compounds/chemical synthesis; Organogold Compounds/pharmacology; Antineoplastic Agents/pharmacology; Cell Line, Tumor; Cytochromes c/drug effects; Drug Stability; Humans; Ligands; Molecular Structure; Phosphoranes/chemistry; Solubility; Thioredoxin-Disulfide Reductase/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apoptosis / Organogold Compounds / Antineoplastic Agents Limits: Humans Language: En Journal: Inorg Chem Year: 2009 Document type: Article Affiliation country: United States

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