Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway.

Kleaveland, Benjamin; Zheng, Xiangjian; Liu, Jian J; Blum, Yannick; Tung, Jennifer J; Zou, Zhiying; Sweeney, Shawn M; Chen, Mei; Guo, Lili; Lu, Min-min; Zhou, Diane; Kitajewski, Jan; Affolter, Markus; Ginsberg, Mark H; Kahn, Mark L

Kleaveland, Benjamin; Zheng, Xiangjian; Liu, Jian J; Blum, Yannick; Tung, Jennifer J; Zou, Zhiying; Sweeney, Shawn M; Chen, Mei; Guo, Lili; Lu, Min-min; Zhou, Diane; Kitajewski, Jan; Affolter, Markus; Ginsberg, Mark H; Kahn, Mark L.

Affiliation

Kleaveland B; Department of Medicine and Cardiovascular Institute, University of Pennsylvania, 421 Curie Blvd., Philadelphia, Pennsylvania 19104, USA.

Nat Med ; 15(2): 169-76, 2009 Feb.

Article in En | MEDLINE | ID: mdl-19151727

Subject(s)

Cardiovascular System/embryology; Carrier Proteins/physiology; Hemangioma, Cavernous, Central Nervous System/physiopathology; Membrane Glycoproteins/physiology; Zebrafish Proteins/physiology; Animals; Carrier Proteins/genetics; Carrier Proteins/metabolism; Hemorrhage/genetics; Humans; KRIT1 Protein; Membrane Glycoproteins/genetics; Membrane Glycoproteins/metabolism; Mice; Microtubule-Associated Proteins/metabolism; Proto-Oncogene Proteins/metabolism; Signal Transduction; Zebrafish Proteins/genetics; Zebrafish Proteins/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Membrane Glycoproteins / Cardiovascular System / Carrier Proteins / Hemangioma, Cavernous, Central Nervous System / Zebrafish Proteins Limits: Animals / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2009 Document type: Article Affiliation country: United States Country of publication: United States

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