Comparison of the electrophysiologically based optimization methods with different pacing parameters in patient undergoing resynchronization treatment.
Annu Int Conf IEEE Eng Med Biol Soc
; 2008: 1741-4, 2008.
Article
in En
| MEDLINE
| ID: mdl-19163016
ABSTRACT
Many studies conducted on patients suffering from congestive heart failure have shown the efficacy of cardiac resynchronization therapy (CRT). The presented research investigates an off-line optimization algorithm based on different electrode positioning and timing delays. A computer model of the heart was used to simulate left bundle branch block (LBBB), myocardial infarction (MI) and reduction of intraventricular conduction velocity in order to customize the patient symptom. The optimization method evaluates the error between the healthy heart and pathology with/without pacing in terms of activation time and QRS length. Additionally, a torso model of the patient is extracted to compute the body surface potential map (BSPM) and to simulate the ECG with Wilson leads to validate the results obtained by the electrophysiological heart model optimization.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cardiac Pacing, Artificial
/
Heart Failure
Type of study:
Evaluation_studies
Limits:
Humans
Language:
En
Journal:
Annu Int Conf IEEE Eng Med Biol Soc
Year:
2008
Document type:
Article
Affiliation country:
Germany