Contribution of globular death domains and unstructured linkers to MyD88.IRAK-4 heterodimer formation: an explanation for the antagonistic activity of MyD88s.

Mendoza-Barberá, Elena; Corral-Rodríguez, María Angeles; Soares-Schanoski, Alessandra; Velarde, Milko; Macieira, Sofia; Messerschmidt, Albrecht; López-Collazo, Eduardo; Fuentes-Prior, Pablo

Mendoza-Barberá, Elena; Corral-Rodríguez, María Angeles; Soares-Schanoski, Alessandra; Velarde, Milko; Macieira, Sofia; Messerschmidt, Albrecht; López-Collazo, Eduardo; Fuentes-Prior, Pablo.

Affiliation

Mendoza-Barberá E; Cardiovascular Research Center and Institut de Recerca, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret 167, 08025 Barcelona, Spain.

Biochem Biophys Res Commun ; 380(1): 183-7, 2009 Feb 27.

Article in En | MEDLINE | ID: mdl-19167362

Subject(s)

Interleukin-1 Receptor-Associated Kinases/metabolism; Myeloid Differentiation Factor 88/metabolism; Amino Acid Sequence; Animals; Dimerization; Glutamic Acid/genetics; Glutamic Acid/metabolism; Humans; Immunity, Innate; Interleukin-1 Receptor-Associated Kinases/chemistry; Interleukin-1 Receptor-Associated Kinases/genetics; Models, Chemical; Molecular Sequence Data; Myeloid Differentiation Factor 88/chemistry; Myeloid Differentiation Factor 88/genetics; Protein Structure, Secondary/genetics; Protein Structure, Tertiary/genetics; Recombinant Proteins/chemistry; Recombinant Proteins/genetics; Recombinant Proteins/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interleukin-1 Receptor-Associated Kinases / Myeloid Differentiation Factor 88 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Biochem Biophys Res Commun Year: 2009 Document type: Article Affiliation country: Spain

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