Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs.
Antimicrob Agents Chemother
; 53(4): 1353-61, 2009 Apr.
Article
in En
| MEDLINE
| ID: mdl-19188385
ABSTRACT
For a panel of 153 Staphylococcus aureus clinical isolates (including 13 vancomycin-intermediate or heterogeneous vancomycin-intermediate and 4 vancomycin-resistant strains), MIC(50)s and MIC(90)s of three novel dihydrophthalazine antifolates, BAL0030543, BAL0030544, and BAL0030545, were 0.03 and 0.25 microg/ml, respectively, for methicillin-susceptible strains and 0.03 and
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Phthalazines
/
Staphylococcus aureus
/
Staphylococcus epidermidis
/
Folic Acid Antagonists
/
Anti-Bacterial Agents
Language:
En
Journal:
Antimicrob Agents Chemother
Year:
2009
Document type:
Article
Affiliation country:
United States