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DYRK1A interacts with the REST/NRSF-SWI/SNF chromatin remodelling complex to deregulate gene clusters involved in the neuronal phenotypic traits of Down syndrome.
Lepagnol-Bestel, Aude-Marie; Zvara, Agnes; Maussion, Gilles; Quignon, Frédérique; Ngimbous, Bedel; Ramoz, Nicolas; Imbeaud, Sandrine; Loe-Mie, Yann; Benihoud, Karim; Agier, Nicolas; Salin, Paul A; Cardona, Ana; Khung-Savatovsky, Suonavy; Kallunki, Pekka; Delabar, Jean-Maurice; Puskas, Laszlo G; Delacroix, Hervé; Aggerbeck, Lawrence; Delezoide, Anne-Lise; Delattre, Olivier; Gorwood, Philip; Moalic, Jean-Marie; Simonneau, Michel.
Affiliation
  • Lepagnol-Bestel AM; INSERM U675, IFR02, Faculté de Médecine Xavier Bichat, Université Paris Diderot-Paris 7, Paris, France.
Hum Mol Genet ; 18(8): 1405-14, 2009 Apr 15.
Article in En | MEDLINE | ID: mdl-19218269
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Transcription Factors / Protein-Tyrosine Kinases / Chromosomal Proteins, Non-Histone / Protein Serine-Threonine Kinases / Down Syndrome / Chromatin Assembly and Disassembly Type of study: Prognostic_studies Limits: Animals Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2009 Document type: Article Affiliation country: France Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Transcription Factors / Protein-Tyrosine Kinases / Chromosomal Proteins, Non-Histone / Protein Serine-Threonine Kinases / Down Syndrome / Chromatin Assembly and Disassembly Type of study: Prognostic_studies Limits: Animals Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2009 Document type: Article Affiliation country: France Country of publication: United kingdom