PAF exerts a direct apoptotic effect on the rat H9c2 cardiomyocytes in Ca2+-dependent manner.

Zhao, Dan; Chu, Wen-Feng; Wu, Ling; Li, Jing; Liu, Qing-Mei; Lu, Yan-Jie; Qiao, Guo-Fen; Wang, Zhi-Guo; Zhang, Zhi-Ren; Yang, Bao-Feng

Zhao, Dan; Chu, Wen-Feng; Wu, Ling; Li, Jing; Liu, Qing-Mei; Lu, Yan-Jie; Qiao, Guo-Fen; Wang, Zhi-Guo; Zhang, Zhi-Ren; Yang, Bao-Feng.

Affiliation

Zhao D; Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, and The Second Affiliated Hospital, Harbin, People's Republic of China.

Int J Cardiol ; 143(1): 86-93, 2010 Aug 06.

Article in En | MEDLINE | ID: mdl-19237210

Subject(s)

Apoptosis/drug effects; Calcium/metabolism; Myocytes, Cardiac; Platelet Activating Factor/pharmacology; Platelet Activating Factor/physiology; Animals; Apoptosis/physiology; Caspase 3/metabolism; Cell Line; Cell Survival/drug effects; Cell Survival/physiology; Chelating Agents/pharmacology; Cytochromes c/metabolism; Egtazic Acid/analogs & derivatives; Egtazic Acid/pharmacology; MAP Kinase Signaling System/drug effects; MAP Kinase Signaling System/physiology; Myocytes, Cardiac/cytology; Myocytes, Cardiac/drug effects; Myocytes, Cardiac/physiology; Rats; p38 Mitogen-Activated Protein Kinases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Platelet Activating Factor / Calcium / Apoptosis / Myocytes, Cardiac Limits: Animals Language: En Journal: Int J Cardiol Year: 2010 Document type: Article Country of publication: Netherlands

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